^#Corresponding author

Lee SC, To M, Papp B, Boulant S, and Toth Z^# (2026) Stage-specific regulation of KSHV infection by HIF-1a. Journal of Virology, 2026 April; 100(4):e0004326. PMID: 41805195

Torma G, Dörmő Á, Fülöp Á, Tombácz D, Mizik M, Pretory AM, Lee SC, Toth Z, Boldogkői Z (2025) Long-read transcriptomics of Caviid gammaherpesvirus 1: compiling a comprehensive RNA atlas. mSystems 2025 Feb 27:e0167824. doi: 10.1128/msystems.01678-24. PMID: 40013795

Jang SJ, Atyeo N, Mietzsch M, Chae MY, McKenna R, Toth Z^#, and Papp B^# (2024) Genome-wide transcriptional roles of KSHV viral interferon regulatory factors in oral epithelial cells. Viruses, 2024, May 25;16(6):846. PMID: 38932139

Prazsák I, Tombácz D, Fülöp Á, Torma G, Gulyás G, Dörmő Á, Kakuk B, Spires LM, Toth Z^#, and Boldogkői Z^# (2024) KSHV 3.0: A state-of-the-art annotation of the Kaposi’s sarcoma-associated herpesvirus transcriptome using cross-platform sequencing. mSystems, 2024 Jan 11:e01007-23. PMID: 38206015

Lee SC, Naik NG, Tombácz D, Gulyás G, Kakuk B, Boldogkői Z, Hall K, Papp B, Boulant S, and Toth Z^# (2023) Hypoxia and HIF-1a promote lytic de novo KSHV infection. Journal of Virology, 2023 Nov; 97(11):e00972-23. PMID: 37909728

Torma G, Tombácz D, Almsarrhad IAA, Csabai Z, Nagy GÁ, Kakuk B, Gulyás G, Spires LM, Gupta I, Fülöp Á, Dörmő Á, Prazsák I, Mizik M, Dani VÉ, Csányi V, Zádori Z, Toth Z^#, and Boldogkői Z^# (2023) Identification of herpesvirus transcripts from genomic regions around the replication origins. Scientific Reports, 2023 Sep 29;13(1):16395. PMID: 37773348

Spires LM, Wind E, PappB, and Toth Z^# (2023) KSHV RTA utilizes the host E3 ubiquitin ligase complex RNF20/40 to drive lytic reactivation. Journal of Virology, 2023 Oct 27:e0138923. PMID: 37888983

Combs LR, Combs R, McKenna R, and Toth Z^# (2023) Protein degradation by gammaherpesvirus RTAs: More than just viral transactivators. Viruses, 2023 Mar 11;15(3):730. PMID: 36992439

Atyeo N, Chae MY, Toth Z, Sharma A, and Papp B (2023) Kaposi’s sarcoma-associated herpesvirus immediate early proteins trigger FOXQ1 expression in oral epithelial cells, engaging in a novel lytic cycle-sustaining positive feedback loop. Journal of Virology, 2023 Mar 30;97(3):e0169622. PMID: 36815831

Naik NG*, Lee SC*, Veronese BHS, Ma Z, and Toth Z^# (2022) Interaction of HDAC2 with SARS-CoV-2 NSP5 and IRF3 is not required for NSP5-mediated inhibition of type I interferon signaling pathway. Microbiology Spectrum. 2022 Oct 26;10(5):e0232222. PMID: 36173315 (Equal contribution*)

Lee SC and Toth Z^# (2022) PRC1-independent binding and activity of RYBP on the KSHV genome during de novo infection. PLoS Pathogens, 2022 Aug 26;18(8):e1010801. PMID: 36026503

Combs LR, Spires LM, Alonso JD, Papp B, and Toth Z^# (2022) KSHV RTA induces degradation of the host transcription repressor ID2 to promote the viral lytic cycle. Journal of Virology, 2022 Jun 22;96(12):e0010122. PMID: 35604218

Kumar A, Grams TR, Bloom DC, and Toth Z^# (2022) Signaling pathway reporter screen with SARS-CoV-2 proteins identifies nsp5 as a repressor of p53 activity. Viruses May 13;14(5):1039. PMID: 35632779

Atyeo N, Rodriguez MD, Papp B^#, and Toth Z^# (2021) Clinical manifestations and epigenetic regulation of oral herpesvirus infections. Viruses 2021 Apr 15;13(4): 681. PMID: 33920978

Naik NG, Lee SC, Alonso JD, and Toth Z^# (2021) KDM2B overexpression facilitates lytic de novo KSHV infection by inducing AP-1 activity through interaction with the SCF E3 ubiquitin ligase complex. Journal of Virology, 2021 May 10;95(11). 95:e00331-21. PMID: 33692209

Kim YJ, Kim Y, Kumar A, Kim CW, Toth Z, Cho NH, and Lee HR (2021) Kaposi’s sarcoma-associated herpesvirus latency-associated nuclear antigen dysregulates expression of MCL-1 by targeting FBW7. PLoS Pathogens, 2021 Jan 20;17(1): e1009179. PMID: 33471866

Naik NG, Nguyen TH, Roberts L, Fischer LT, Glickman K, Golas G, Papp B^#, and Toth Z^# (2020) Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV. PLoS Pathogens, 2020 Jan 10;16(1):e1008268. PMID: 31923286

Golas G, Jang SJ, Naik NG, Alonso JD, Papp B, and Toth Z^# (2020) Comparative analysis of the viral interferon regulatory factors of KSHV for their requisite for virus production and inhibition of the type I interferon pathway. Virology, 2020 Feb:541:160-173. PMID: 32056714

Golas G, Alonso JD, and Toth Z^# (2019) Characterization of de novo lytic infection of dermal lymphatic microvascular endothelial cells by Kaposi’s sarcoma-associated herpesvirus. Virology, 2019 Oct:536:27-31. PMID: 31394409

Papp B^#, Motlagh N, Smindak RJ, Jang SJ, Sharma A, Alonso JD, and Toth Z^# (2019) Genome-wide identification of direct RTA targets reveals key host factors for KSHV lytic reactivation. Journal of Virology, 2019 Feb 19;93(5):e01978-18. PMID: 30541837

Brice DC, Toth Z, and Diamond G (2018) LL-37 disrupts the Kaposi’s sarcoma-associated herpesvirus envelope and inhibits infection of oral epithelial cells. Antiviral Research, 2018 Oct:158:25-33. PMID: 30076864

Toth Z^#, Smindak R, and Papp B (2017) Inhibition of the lytic cycle of Kaposi’s sarcoma-associated herpesvirus by cohesin factors following de novo infection. Virology, 2017 Dec:512:25-33. PMID: 28898712

Toth Z^#, Papp B, Brulois KF, Choi YJ, Gao SJ and Jung JU^# (2016) LANA-mediated recruitment of Polycomb Repressive Complexes onto the KSHV genome during de novo. PLoS Pathogens, 2016 Sep 8;12(9):e1005878. PMID: 27606464

Brulois KF, Wong LY, Lee HR, Sivadas P, Ensser A, Feng P, Gao SJ, Toth Z^# and Jung JU^# (2015) The association of Kaposi’s sarcoma-associated herpesvirus ORF31 with ORF34 and ORF24 is critical for late gene expression. Journal of Virology, 2015 Jun;89(11):6148-54. PMID: 25810551

Brulois KF, Toth Z, Wong LY, Feng P, Gao SJ, Ensser A and Jung JU (2014) KSHV K3 and K5 ubiquitin E3 ligases have stage-specific immune evasion roles during lytic replication. Journal of Virology, 2014 Aug;88(16):9335-49. PMID: 24899205

Lee HR, Doğanay S, Chung B, Toth Z, Brulois K, Lee S, Kanketayeva Z, Feng P, Ha TJ and Jung JU. (2014) Kaposi’s Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 (vIRF4) targets expression of cellular IRF4 and the Myc gene to facilitate lytic replication. Journal of Virology, 2014 Feb;88(4):2183-94. PMID: 24335298

Toth Z^#, Brulois K and Jung JU. (2014) Kaposi’s Sarcoma-Associated Herpesvirus: Biology of a Human Tumor Virus. Reference Module in Biomedical Sciences. 10.1016/B978-0-12-801238-3.00082-9. Book chapter.

Toth Z^#, Brulois K and Jung JU. (2013) The chromatin landscape of Kaposi’s sarcoma-associated herpesvirus. Viruses. 2013 May; 5(5): 1346-73. PMID: 23698402

Wong LY, Toth Z, Brulois KF, Inn KS, Lee SH, Lee HR and Jung JU (2013) Molecular Mimicry by γ-2 Herpesviruses to Modulate Host Cell Signaling Pathways. In: Brinkworth J., Pechenkina K. (eds) Primates, Pathogens, and Evolution. Developments in Primatology: Progress and Prospects. Springer, New York, NY. Book chapter.

Toth Z^#, Brulois KF, Lee HR, Izumiya Y, Tepper C, Kung HJ, Jung JU^# (2013) Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection. PLoS Pathogens. 2013 Dec; 9(12): e1003813. PMID: 24367262

Wong LY, Brulois KF, Toth Z, Lee SH, Inn KS, O’Brien K, Lee HR, Cesarman E Jung JU. (2013) KSHV K4.2 immediate early gene product regulates immunoglobulin secretion and calcium homeostasis by interacting with and inhibiting pERP1. Journal of Virology, 2013 Nov;87(22):12069-79. PMID: 23986581

Lee SH, Toth Z, Wong LY, Brulois K, Nguyen J, Lee JY, Zandi E, Jung JU. (2012) Novel Phosphorylations of IKKγ/NEMO. MBio, 2012 Nov 6;3(6):e00411-12. PMID: 23131831

Toth, Z., Brulois K, Wong LY, Lee HR, Chung B, and Jung JU. (2012) NELF-mediated suppression of RNA polymerase II elongation of Kaposi’s sarcoma-associated herpesvirus lytic gene expression. Journal of Virology, 2012 Sep;86(18):9696-707. PMID: 22740393

Brulois KF, Chang H, Lee AS, Ensser A, Wong LY, Toth Z, Lee SH, Lee HR, Myoung J, Ganem D, Oh TK, Kim JF, Gao SJ, and Jung JU. (2012) Construction and manipulation of a new Kaposi’s sarcoma-associated herpesvirus Bacterial artificial chromosome clone. Journal of Virology, 2012 Sep;86(18):9708-20. PMID: 22740391

He M, Zhang W, Bakken T, Schutten M, Toth Z, Jung JU, Gill P, Cannon M, and Gao SJ. (2012) Cancer Angiogenesis Induced by Kaposi Sarcoma-Associated Herpesvirus Is Mediated by EZH2. Cancer Research, 2012 Jul 15;72(14):3582-92. PMID: 22593192

Lee HR, Choi WC, Lee S, Hwang J, Hwang E, Guchhait K, Haas J, Toth Z, Jeon YH, Oh TK, Kim MH, Jung JU. (2011) Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein. Nat. Struct. Mol. Biol, 2011 Nov 6;18(12):1336-44. PMID: 22056774

Inn KS, Lee SH, Rathbun JY, Wong LY, Toth Z, Machida K, Ou JH, Jung JU. (2011) Inhibition of RIG-I mediated signaling by Kaposi’s sarcoma-associated herpesvirus-encoded deubiquitinase ORF64. Journal of Virology, 2011 Oct;85(20):10899-904. PMID: 21835791

Jeong JH, Bhatia A, Toth Z, Oh S, Inn KS, Liao CP, Roy-Burman P, Melamed J, Coetzee GA, Jung JU. (2011) TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth. PLoS One, 2011 Jan 18;6(1):e16205. PMID: 21267413

Toth Z, Maglinte DT, Lee SH, Lee HR, Wong LY, Brulois KF, Lee S, Buckley JD, Laird PW, Marquez VE and Jung JU. (2010) Epigenetic analysis of KSHV latent and lytic genomes. PLoS Pathogens, 2010 Jul 22;6(7): e1001013. PMID: 20661424

Lee H, Toth Z, Shin YC, Lee J, Chang H, Gu W, Oh TK, Kim MH and Jung JU. (2009) Kaposi’s sarcoma-associated herpesvirus viral Interferon Regulatory Factor 4 targets MDM2 to deregulate the p53 tumor suppressor pathway. Journal of Virology, 2009 Jul 83(13):6739-47. PMID: 19369353

Toth Z and Stamminger T. (2008) The human cytomegalovirus regulatory protein UL69 and its effect on mRNA export. Frontiers in Bioscience, 2008 Jan 1:13: 2939-49. PMID: 17981767

Lischka P, Thomas M, Toth Z, Mueller R and Stamminger T. (2007) Multimerization of human cytomegalovirus regulatory protein UL69 via a domain that is conserved within its herpesvirus homologues. Journal of General Virology, 2007 Feb;88(Pt 2):405-410. PMID: 17251556

Toth Z, Lischka P, and Stamminger T. (2006) RNA-binding of the human cytomegalovirus transactivator protein UL69, mediated by arginine-rich motifs, is not required for nuclear export of unspliced RNA. Nucleic Acids Research, 2006 Feb 25;34(4):1237-49. PMID: 16500893

Lischka P, Toth Z, Thomas M, Mueller R, and Stamminger T. (2006) The UL69 transactivator protein of human cytomegalovirus interacts with DExD/H-box RNA helicase UAP56 to promote cytoplasmic accumulation of unspliced RNA. Mol. Cell. Biol. 2006 Mar;26(5):1631-43. PMID: 16478985

Raab S, Toth Z, Groot C, Stamminger T, and Hoth S. (2006) ABA-responsive RNA-binding proteins are involved in chloroplast and stromule function in Arabidopsis seedlings. Planta, 2006 Sep;224(4):900-14. PMID: 16633814

Papai G, Komonyi O, Toth Z, Pankotai T, Muratoglu S, Udvardy A, and Boros I. (2005) Intimate relationship between the genes of two transcriptional coactivators, ADA2a and PIMT, of Drosophila. Gene 2005 Mar 28:348:13-23. PMID: 15777699